Profit Margin / ROI % for High Ticket Items

Is there a target profit margin or ROI you look for when vetting products? What is your target? Does that change for large ticket items?

I typically look for 20% profit margin including 15% ACOS for ppc. However, that’s for products that sell for $25-$30.

I’m looking at selling a product that could sell for ~$2,500 and my expected profit is $300, not as high profit margin %, but it still feels like something I should pursue. Thoughts?